Garlic (Allium sativum Linn) has activity against e. coli bacteria, namely as the killer of bacterial growth (bakterisidal). This can be explained from the bacteria and the active substances contained in garlic. Allisin antibacterial compounds in garlic (Heinrich et al., 2010). According to Durairaj et al., (2010) allisin inhibit the production of RNA synthesis and inhibition of lipid, this causes the amino acids and proteins cannot be produced as well as biolayer phospholipids from cell walls cannot be formed, so that bacteria on the growth and development will not occur. This shows that allisin showed antibacterial activity against gram positive bacteria and gram negative (Saravanan et al., 2010). Allisin have antimicrobial activity. Antibacterial activity of garlic in large part because allicin that appears when garlic is broken. Allisin in the form of pure have antibacterial with a broad spectrum, including on the e. coli strain enterotoksigenik multi-drug resistant. Allisin reactive sulfur compounds and tend to be unstable, have the ability to fight biological catalysts (enzymes), especially the inside or under a layer of bacteria needed for the growth and reproduction of bacteria.
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