SUMMARYA. Background Malaria is the major infectious diseases in the world, the majority of deaths caused by malaria in malaria because Plasmodium falciparum infection. (Harijanto et al., 2009). Malaria remains a major public health problem in Jayapura Regency. In 2010, data from the Department of health of Papua Province there were 21.971 cases of malaria in the city of Jayapura. (TOPTV,2012). General Hospital area of Jayapura (PROVINCIAL HOSPITAL) is a hospital type B with reference number of terdiagnosa falciparum malaria patients and given treatment using artesunat injection and dihydroartemisinin-piperakuin (DHP) from January to May 2011 amounting to 150 patients (Hadalia, 2011; Wanggai, 2011). The use of artesunat injection and DHP and primakuin since last few years used in cases of severe malaria in the PROVINCIAL HOSPITAL in Jayapura. Based on the above then need to do a research to evaluate the efficacy and side effects of the drug combination artesunat injection and DHP and primakuin on patients with severe malaria in the PROVINCIAL HOSPITAL in Jayapura.
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