The results of drag zone or zones clear Serratia marcescens and established between e. coli there is a significant difference of each spice extracts. It proves that each antibacterial compounds work specifically to inhibit the growth of certain bacteria. Antimicrobial compounds inhibitory power on spices that are used still belongs to low to inhibit the growth of e. coli, since E coli bacteria was coliform which can hold live in the media that a lack of nutrients. In addition, E coli is a bacteria gram negativ that have cell walls composed of three layered lipoproteins, outer membrane phospholipids and lipopolysaccharide, and lipid content on cell walls ranged from 11 to 22% antimicrobial compounds so difficult to penetrate the cell wall [4]. While the antimicrobial compound drag power, against growth of Serratia marcescens is quite effective on the nutmeg seed whereas in other spices that still belongs to the weak.
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