There are about 50,000 kinds of vertebrate animals (vertebrates) that are known to date. They live in all biological environment both on land, sea water, fresh water, and air. Although a variety of body shapes and sizes but have the same basic body structure. Vertebrate generally consists of head and body. The body composed of the chest and abdominal cavity. Vertebrate animals that live on land usually have a neck. The spine is derived from the development of the body axis of the primary backers or notochord (chorda dorsalis). Notochord vertebrates exist only in embryonic period, as adults will experience a reinforcement become a secondary backup system of the body, namely the spine (vertebrae). In the classification system, the vertebrate is a subphylum of the phylum Chordata. Chordates include the animals that have the following characteristics: • Have a notochord, which is rod-shaped skeleton hard but pliable. Notochord lies between the digestive tract and nerve cords, extending along the axis of the body forming the skeleton. • Have a single nerve cord, dorsal to the notochord hollow lies, and have enlarged anterior end in the form of the brain. • It has a tail that extends posteriorly to anus. • have pharyngeal slits. Vertebrates consists of five classes of Pisces, amphibia, reptiles, and mammals aves
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